CarboDB Capsular polysaccharide 1998

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Capsular polysaccharide

[edit] Carbohydrate Class

Capsular polysaccharide

[edit] Source Microbe

Streptococcus pneumoniae serotype 6B

[edit] Basic Structure

The capsular polysaccharide consists of the following residues : -2)-α-D-Galp-(1-->3)-α-D-Glcp-(1-->3)-α-L-Rhap-(1-->4)-D-Rib-ol-(5-P-

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

Glycoconjugates

[edit] Carrier Name

Diphtheria toxin mutant (CRM197)

[edit] Conjugation Method

N/A

[edit] Antibodies

Mab Hyp6BG8

[edit] Antibody type and class

IgG1

[edit] Assay System

Sandwich ELISA, opsonization assays

[edit] Cross-reactivity

This Mab cross-reacted with strain 6A

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This Mab had opsonophagocytic activity

[edit] Weblink

PubMed Central

[edit] External Links

• BCSDB Structural Detail

• Link to CarboDB database