Embryonic liver differentiation factor 10;Precursor

From DrugPedia: A Wikipedia for Drug discovery

Jump to: navigation, search

Contents

[edit] Source Organism

Homo sapiens (Human).

[edit] Taxomomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.

[edit] Subcellular Localization

Membrane; Single-pass type I membrane protein (Potential).

[edit] Developmental Stage

[edit] Similarity

[edit] Post translational Modification

Phosphorylated.

[edit] Function

Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS).