Nuclear receptor subfamily 1 group B member 3-B
From DrugPedia: A Wikipedia for Drug discovery
Contents |
[edit] Source Organism
Danio rerio (Zebrafish) (Brachydanio rerio).
[edit] Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio.
[edit] Subcellular Localization
Nucleus.
[edit] Developmental Stage
Expressed both maternally and zygotically.
[edit] Similarity
Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.
[edit] Post translational Modification
[edit] Function
This is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression (By similarity).