PolysacDB Arabinogalactan and arabinomannan 1744
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Arabinogalactan and arabinomannan
[edit] Carbohydrate Class
Miscellaneous
[edit] Source Microbe
Mycobacterium tuberculosis
[edit] Basic Structure
Mycobacterial lipoarabinomannan is a phosphatidylinositol anchored lipoglycan that consists of an α1-->6 linked backbone, substituted to varying degrees at position 2 with single α-Man residues, and directly attached to position 6 of the myo-inositol of a phosphatidylinositol (PI) anchor
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
M. tuberculosis culture filtrate
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab TB-C-1
[edit] Antibody type and class
IgM
[edit] Assay System
ELISA, immunoblotting, Immunosorbent affinity chromatography and Immunoelectrophoresis
[edit] Cross-reactivity
This Mab is highly cross-reactive and cross-reacted with M. kansasii, M. gordonae, M. scrofulaceum and M. intracellulare
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
This Mab would allow the purification of important mycobacterial antigens antigens
