PolysacDB Band 1 glycolipid antigen 1896

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Band 1 glycolipid antigen

[edit] Carbohydrate Class

Miscellaneous

[edit] Source Microbe

Paracoccidiodes brasiliensis

[edit] Basic Structure

The structure of glycolipid antigen is Galfβ1->6(Manpα1-->3)Manpβ1-->2Ins

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

Whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab MEST1

[edit] Antibody type and class

IgG3

[edit] Assay System

High performance thin layer chromatography immunostaining, solid phase radioimmunoassay

[edit] Cross-reactivity

This Mab cross-reacted with promastigotes of Leishmania major and epimastigotes of Trypanosoma cruzi

[edit] Proposed epitopes

Terminal residue of β-D-galactofuranose of Band 1 seems to be a part of the epitope

[edit] Proposed Utility

MAb MEST-1 can be a valuable tool in studies of biological role of galactofuranose residues

[edit] Weblink

PubMed

[edit] External Links

• IEDB Epitopic Detail

• Link to PolysacDB database