PolysacDB Capsular polysaccharide 1464
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Capsular polysaccharide
[edit] Carbohydrate Class
Capsular polysaccharide
[edit] Source Microbe
Enterococcus faecalis 12030
[edit] Basic Structure
Glycerol teichoic acid-like molecules with a carbohydrate backbone structure of 6-α-D-glucose- 1-->2 glycerol-3-PO4 with substitution on carbon 2 of the glucose with an α-2-1-D-glucose residue
[edit] Proposed functions
These polysaccharides are major virulence factors
[edit] Antigenic Nature used to produce antibodies
gentamicin-killed Enterococcus faecalis strains
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Polysera
[edit] Antibody type and class
N/A
[edit] Assay System
Opsonophagocytic assay, immunoelectron microscopy
[edit] Cross-reactivity
This antisera reacted with the homologous strain (12030) and mediated opsonic killing of 33% of all strains tested. In addition, this serum killed two (28%) of seven vancomycin-resistant Enterococcus faecium strains
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
This antisera was opsonophagcytic
