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- B Cells and T Cells ... ling alone results in anergy. The signalling pathways downstream from both CD28 and the T cell receptor involve many proteins. ... vation of the T cell, such as OX40 and ICOS, but these largely depend upon CD28 for their expression. The second signal licenses the T cell to respond to ...15 KB (2456 words) - 10:44, 18 August 2008
- TGN1412 '''TGN1412''' (also known as '''CD28-SuperMAB''') is the working name of an [[immunomodulator]]y drug which was ... ... onal antibody]] that not only binds, but is a strong [[agonist]] for the [[CD28]] receptor of the [[immune system]]'s [[T cell]]s.<ref name="Lin2004">{{ci ...29 KB (4350 words) - 08:44, 22 August 2008
