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  • Drug Discovery
    ... ll interfering RNA (siRNA), which initiates the cleavage of the homologous mRNA in a complex named the RNA-induced silencing complex (RISC). ... lls leads to inhibition of the biological function encoded in the targeted mRNA-the underlying concept of RNAi therapeutics. For example, this approach is ...
    23 KB (3467 words) - 03:48, 1 September 2008
  • RNAi therapeutics
    ... tly bind to the mRNA in sequence specific manner to degrade or supress the mRNA. The short 20-25 bp fragments are known as small interfering RNA (siRNA) w ...
    3 KB (501 words) - 09:20, 11 August 2008
  • Protein structure
    ... ucleotide]]s in [[DNA]] is [[Transcription (genetics)|transcribed]] into [[mRNA]], which is read by the ribosome in a process called translation. The sequ ...
    27 KB (4092 words) - 12:18, 4 December 2008
  • Genomics
    ... ules and ever more complex systems. Three levels of genomic analysis - the mRNA level, the protein level, and the level of low molecular weight intermedia ...
    5 KB (708 words) - 07:03, 18 August 2008
  • DNA
    ... rase at work.png|thumb|left|300px|[[T7 RNA polymerase]] (blue) producing a mRNA (green) from a DNA template (orange).<ref>Created from [http://www.rcsb.or ...
    82 KB (11827 words) - 06:08, 20 August 2008
  • BioBrick
    ... tions per second, the number of times a ribosome passes a certain point on mRNA each second.[5]
    4 KB (618 words) - 10:20, 19 August 2008
  • RNA
    [[Image:Pre-mRNA-1ysv.png|thumb|200px|A hairpin loop from a pre-mRNA. Notice its nitrogen-rich (blue) bases and oxygen-rich (red) backbone.]] ... example, a [[poly(A) tail]] and a [[5' cap]] are added to eukaryotic [[pre-mRNA]].
    31 KB (4467 words) - 07:24, 20 August 2008
  • Proteomics
    ... produced in a cell needs to be determined (in the past this was done by [[mRNA]] analysis - but even this should be confirmed by confirming the proteins ... ... ves only a rough estimate of its level of expression into a protein. An [[mRNA]] produced in abundance may be degraded rapidly or translated inefficientl ...
    16 KB (2303 words) - 09:50, 17 September 2008
  • Drug design
    ... as small molecules. There have also been suggestions to make these using [[mRNA]]. [[Gene silencing]] may also have therapeutical applications.
    6 KB (827 words) - 06:06, 17 September 2008
  • Toxicogenomics
    ... is the study of all the genes of a cell, or tissue, at the DNA (genotype), mRNA (transcriptome), or protein (proteome) levels. Genomics methodologies are ...
    6 KB (772 words) - 04:56, 26 August 2008
  • Metabonomics
    ... organism, which are the end products of its gene expression. Thus, while [[mRNA]] [[gene expression]] data and [[proteomics|proteomic]] analyses do not te ...
    25 KB (3638 words) - 04:58, 26 August 2008
  • Datasets in Bioinformatics
    ... nomic sequences (h178) coding for single complete genes for which both the mRNA and the coding exons are known. Second, a semi-artficial set of genomic se ...
    16 KB (2424 words) - 11:41, 5 September 2008
  • Gene Prediction Methods
    ... PLICEPREDICTOR||a method to identify potential splice sites in (plant) pre-mRNA by sequence inspection using Bayesian statistical models ||[http://gremlin ...
    4 KB (643 words) - 08:39, 5 September 2008
  • MRNA Interferases from Mycobacterium tuberculosis
    '''mRNA Interferases from Mycobacterium tuberculosis : a drug candidate for tube ... ... get longer RNA sequences may alter protein expression through differential mRNA degradation, a regulatory mechanism that may allow adaptation to environme ...
    5 KB (770 words) - 14:10, 9 September 2008
  • Mrna interferases
    '''mRNA Interferases from Mycobacterium tuberculosis : a drug candidate for tube ... ... get longer RNA sequences may alter protein expression through differential mRNA degradation, a regulatory mechanism that may allow adaptation to environme ...
    3 KB (423 words) - 03:34, 9 September 2008
  • RNAi
    ... posttranscriptional inhibition of gene expression via an increased rate of mRNA degradation. This phenomenon was called cosuppression of gene expression, ... * Silencing was specific for an mRNA homologous to the dsRNA; other mRNAs are not at all affected.
    21 KB (3143 words) - 10:35, 9 September 2008
  • Non-Coding RNA
    ... coding RNA (npcRNA), non-messenger RNA (nmRNA), small non-messenger RNA (snmRNA), or functional RNA (fRNA). The DNA sequence from which a non-coding RNA i ... ... ion other than coding for protein even though they are on a protein-coding mRNA, for example riboswitches and the SECIS element.
    6 KB (937 words) - 08:41, 10 September 2008
  • HIV
    ... age, the structural proteins Gag and Env are produced from the full-length mRNA. The full-length RNA is actually the virus genome; it binds to the Gag pro ... ... bind to any appropriate RNA whereas HIV-2 will preferentially bind to the mRNA which was used to create the Gag protein itself. This may mean that HIV-1 ...
    42 KB (6578 words) - 18:15, 12 September 2008
  • Estradiol
    ... [[gene transcription]] which leads to formation of [[messenger RNA]]. The mRNA interacts with [[ribosome]]s to produce specific proteins that express the ...
    21 KB (2912 words) - 05:26, 24 February 2009
  • Serotonin
    ... Antidepressant Treatments on Serotonin Transporter Function, Density, and mRNA Level. Journal of Neuroscience, 1999, 19(23):10494-10501. http://www.jneu ...
    38 KB (5178 words) - 12:28, 19 February 2009

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