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- ADMET The substances resulting from the metabolism called metabolites can be inactive or having same therapeutic activity as the drug. Prodrugs ... Most drugs, particularly water-soluble drugs and their metabolites, are eliminated largely by the kidneys in urine. Some drugs are eliminated ...3 KB (515 words) - 12:01, 29 August 2008
- Toxicology ... eversible, include absorption, transport, metabolism to more or less toxic metabolites, excretion, interaction with cellular macromolecules and other modes of to ...5 KB (751 words) - 08:13, 19 August 2008
- Genomics ... l, the protein level, and the level of low molecular weight intermediates (metabolites) - combine to provide an understanding of whole organism functioning. Syst ...5 KB (708 words) - 07:03, 18 August 2008
- Systems biology ... to the function and behavior of that system (for example, the enzymes and metabolites in a metabolic pathway). * Metabolomics: identification and measurement of all small-molecules metabolites within a cell or tissue18 KB (2525 words) - 05:00, 12 September 2008
- Metabonomics ... 5-28, April 25, 2005</ref> The metabolome represents the collection of all metabolites in a biological organism, which are the end products of its gene expressio ... ... eadily enough, it is not currently possible to analyse the entire range of metabolites by a single analytical method. In January [[2007]], scientists at the [[Un ...25 KB (3638 words) - 04:58, 26 August 2008
- Abacavir ... lic acid metabolite, 36% 5'-glucuronide metabolite, 15% unidentified minor metabolites). Fecal (16%)7 KB (1000 words) - 03:50, 27 August 2008
- Nonribosomal peptide '''Nonribosomal peptide'''s (NRP) are a class of [[peptide]] [[secondary metabolites]], usually produced by [[microorganism]]s like [[bacterium|bacteria]] and ... Due to the similarity with polyketide synthetases (PKS), many secondary metabolites are, in fact, fusions of NRPs and polyketides. In essencce, this occurs w ...9 KB (1134 words) - 09:44, 17 September 2008
- Medicines of Comman use ... 100% is recovered in the urine within the first day, primarily as inactive metabolites. 5% is excreted as unchanged drug.18 KB (2902 words) - 15:23, 29 August 2008
- Pharmacognosy Most bioactive compounds of natural origin are secondary metabolites, i.e. species-specific chemical agents that can be grouped into various ca ...14 KB (2053 words) - 04:23, 1 September 2008
- Natural product drug discovery ... e chemical agents produced by living organisms (particularly the secondary metabolites) have evolved over millennia under the evolutionary pressure, and are ther ... ... portant source of starting material for drug discovery. A different set of metabolites is usually produced in the different anatomical parts of the plant (e.. ro ...13 KB (1907 words) - 06:09, 17 September 2008
- Basics of Patent Law in India ... ation- For the purposes of this clause, salts, esters, ethers, polymorphs, metabolites, pure form, particle size, isomers, mixtures of isomers, complexes, combin ...21 KB (3406 words) - 04:12, 8 September 2008
- Hormone-Receptor Database [http://www.lipidmaps.org/] The '''LIPID MAPS'''(LIPID Metabolites And Pathways Strategy) structure database .8 KB (1083 words) - 08:58, 30 September 2008
- Indian Patent (Amendment) Act -2005 Explanation to Section 3 (d): "Salts, esters, ethers, polymorphs, metabolites, pure form, particle size, isomers, mixtures of isomers, complexes, combin ...10 KB (1581 words) - 08:29, 23 September 2008
- Analysis of Metabolic ‘Choke’ and ‘Load’ points as Drug Targets in Pathogenic Bacteria ... d could be seen in the case of the citrate cycle where most of the enzymes/metabolites have high load values.3 KB (480 words) - 12:38, 27 September 2008
- Estradiol ... o mammalian sex differentiation is that estradiol is one of the two active metabolites of testosterone in males (the other being [[dihydrotestosterone]]), and si ...21 KB (2912 words) - 05:26, 24 February 2009
- Ethinyl Estradiol ... m in the liver involving the [[cytochrome P450]] 3A4 isoenzyme. EE and its metabolites are in excreted with the bile. Due to the effect of [[enterohepatic circu ...12 KB (1540 words) - 09:12, 24 February 2009
- Levodopa Metabolites are dopamine and homovanillic acid (HVA). Extensively metabolized (greater ...6 KB (710 words) - 09:10, 24 October 2008
- Naproxen ... (66% to 92%). Naproxen t ½ is 12 to 17 h; Cl is 0.13ߙmL/min/kg; t ½ of metabolites and conjugates is less than 12 h. Metabolites and conjugates may accumulate.7 KB (978 words) - 04:34, 26 October 2008
- Scopolamine Less than 10% of the total dose is excreted in urine as parent and metabolites over 108 h; t ½ is 9.5 h.10 KB (1339 words) - 05:04, 26 October 2008
- Dinoprost t ½ is 2.5 to 5 min. Metabolites excreted in the urine.5 KB (669 words) - 05:38, 27 October 2008
