Spinosine

Spinosine
Systematic (IUPAC) name
(13aS)-2,3-dimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-10,11-diol
Identifiers
CAS number	?
ATC code	?
PubChem	177294
Chemical data
Formula	C₁₉H₂₁NO₄
Mol. mass	327.37434
SMILES	eMolecules & PubChem
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

[edit] Description

Spinosine alkaloids obtained from the bark of Annona spinescens.it showed the trypanocidal and antileishmanial activities.

*Molecular Weight

327.37434

*Molecular Formula

C₁₉H₂₁NO₄

*IUPAC NAME

(13aS)-2,3-dimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-10,11-diol

*Canonical Smiles

COC1=C(C=C2C3CC4=CC(=C(C=C4CN3CCC2=C1)O)O)OC

*Isomeric Smiles

COC1=C(C=C2[C@@H]3CC4=CC(=C(C=C4CN3CCC2=C1)O)O)OC

*XLogP

2.5

*Topological Polar Surface Area

62.2