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  • Cimetidine
    ... fically [[CYP1A2]], [[CYP2C9]], [[CYP2C19]], [[CYP2D6]], [[CYP2E1]], and [[CYP3A4]]). This inhibition forms the basis of the numerous [[drug interaction]]s ...
    8 KB (1141 words) - 05:03, 25 August 2008
  • Progestrone
    ... ds, and drug molecules. The microsomal, membrane-associated, P450 isoforms CYP3A4, CYP2D6, CYP2C9, CYP2C19, CYP2E1, and CYP1A2 are responsible for the oxida ...
    8 KB (1073 words) - 09:35, 19 February 2009
  • Betamethasone
    | metabolism = [[hepatic]] [[CYP3A4]]
    5 KB (696 words) - 04:24, 20 February 2009
  • Budesonide
    | metabolism = Hepatic [[CYP3A4]]
    5 KB (647 words) - 05:00, 20 February 2009
  • Flumethasone
    | metabolism = [[Liver|Hepatic]], [[CYP3A4]]-mediated
    3 KB (368 words) - 10:53, 10 December 2009
  • Fluocinolone Acetonide
    | metabolism = [[Liver|Hepatic]], [[CYP3A4]]-mediated
    3 KB (427 words) - 04:47, 25 February 2009
  • Codeine
    ... occurs in the liver and is catalysed by the cytochrome P450 enzyme CYP2D6. CYP3A4 produces norcodeine and UGT2B7 conjugates codeine, norcodeine and morphine ...
    23 KB (3399 words) - 04:10, 29 April 2009
  • Buprenorphine
    ... first-pass metabolism. Buprenorphine is metabolised by the liver, via the CYP3A4 isozyme of the cytochrome P450 enzyme system, into norbuprenorphine (by N- ...
    14 KB (2048 words) - 09:16, 30 April 2009
  • Steroid and xenobiotic receptor;SXR
    ... ts natural ligand is probably pregnane. Binds to a response element in the CYP3A4 and ABCB1/MDR1 genes promoter. Activates its expression in response to a w ...
    727 B (85 words) - 04:43, 17 December 2009
  • Orphan nuclear receptor PXR
    ... ts natural ligand is probably pregnane. Binds to a response element in the CYP3A4 and ABCB1/MDR1 genes promoter. Activates its expression in response to a w ...
    779 B (89 words) - 04:44, 17 December 2009
  • Orphan nuclear receptor MB67
    ... e phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.
    799 B (91 words) - 04:45, 17 December 2009

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